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Pre-seed investors in healthcare and life sciences

49 firms in the directory fund healthcare and life sciences companies at pre-seed. Firms that write the first institutional cheque, usually before there is revenue to underwrite.

Where these firms are

  • California 8
  • United Kingdom 6
  • Illinois 4
  • New York 4
  • United States, state not given 3
  • Canada 2

Head office location. Most firms invest well outside it.

1517 Fund

Venture capital

San Francisco, California, USA


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences

Backs dropouts and non-credentialed founders working on hard science and deep-tech problems at the idea/R&D stage.

3CC | Third Culture Capital

Venture capital

Boston, Massachusetts, USA


Stages

Pre-seedSeed

Sectors

Healthcare & Life Sciences

Immigrant-founded, physician-led seed-stage healthcare VC backing 'Third Culture' founders innovating at the intersection of culture and care delivery.

A-Level Capital

Venture capital

Baltimore, MD, USA


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services

Student-run VC funding and supporting the Johns Hopkins entrepreneurial ecosystem.

Anti Fund Investment Fund

Venture capital

Miami, Florida, USA


Stages

GrowthPre-seedSeedSeries BSeries C

Sectors

Software & Internet · Healthcare & Life Sciences · Transportation & Logistics · Education

Creator-economy-backed venture fund (Geoffrey Woo, Jake & Logan Paul) pairing capital with attention/distribution for frontier-tech startups.

Bethnal Green Ventures

Venture capital

London, UK


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Environmental & Safety

Back ambitious founders using technology to tackle social and environmental problems.

Better Ventures

Venture capital

Oakland, CA, USA


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Environmental & Safety

Backs mission-driven founders using AI/software/biotech to build sustainable industry, improve human health, and equip the workforce.

BlueYard Capital

Venture capital

Berlin, Germany


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Industrials & Manufacturing

Backs founders building frontier technologies that 'move us toward utopia' or 'hold the line against oblivion' - civilization-scale deep tech.

Boost VC

Venture capital

San Mateo, CA, USA


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Industrials & Manufacturing

Boost VC is a pre-seed venture fund making generalist deep-tech bets on startups aiming to make a billion lives better.

BrandProject LP

Venture capital

Toronto, Canada


Stages

Pre-seedSeedSeries A

Sectors

Healthcare & Life Sciences · Consumer & Retail · Food & Beverage

Acts as an operational co-founder backing founders building category-defining consumer companies grounded in real consumer insight, from pre-seed to Series A.

Brightside

Venture capital

Toronto, Ontario, Canada


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Consumer & Retail · Education

Early-stage fund backing founders building technology that disrupts incumbents in foundational, everyday consumer industries across North America.

CincyTech USA

Venture capital

Cincinnati, Ohio


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Industrials & Manufacturing

Regional early-stage venture firm formed by the Cincinnati Chamber, Cincinnati Children's and the University of Cincinnati to fill the high-risk seed capital gap and commercialise regional research;…

Club degli Investitori

Venture capital

Turin, Italy


Stages

GrowthPre-seedSeedSeries ASeries BSeries C

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services · Food & Beverage · Real Estate · Education

Italy's most active business angel network, with 400+ member entrepreneurs and professionals syndicating capital, network and operating expertise into Italian-founded startups and innovative SMEs.

CoFound

Venture capital

New York, NY, United States


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services

Solo-GP seed fund that invests then works hands-on with founders to build a repeatable, formalised sales motion and revenue engine.

Connect Ventures

Venture capital

London, United Kingdom


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services · Environmental & Safety

Backs opinionated 'product founders' from day zero, often leading first rounds at the idea stage.

Connecticut Innovations

Venture capital

New Haven, CT, United States


Stages

GrowthPre-seedSeedSeries BSeries C

Sectors

Software & Internet · Healthcare & Life Sciences

Connecticut's state-backed venture arm and the state's leading source of equity financing for innovative growth companies, pairing capital with mentorship and an in-state network across several…

Core Innovation Capital

Venture capital

Los Angeles, California


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services · Energy & Utilities

Backs founders modernising the infrastructure that powers wealth and health for the mass market, on the thesis that serving everyday Americans profitably produces outsized venture returns.

CREANDUM

Venture capital

Stockholm, Sweden (offices in Berlin, London and San Francisco)


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services · Consumer & Retail

Backs European technology founders early - 'before it's obvious' - and supports them from seed through scale (portfolio includes Spotify, Klarna, Depop, Factorial).

Divergent Capital

Venture capital

New York, New York


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Industrials & Manufacturing · Energy & Utilities · Transportation & Logistics

High-conviction pre-seed fund led by two female operator-investors, leading first rounds for 20 to 25 science and engineering founders outside traditional Silicon Valley networks.

Expon Capital

Venture capital

Luxembourg


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services

Backs early-stage startups with global ambitions and a Luxembourg link; 'doesn't wait for consensus.'

Fusion Fund

Venture capital

Palo Alto, California, USA


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Industrials & Manufacturing

Palo Alto VC founded by Lu Zhang backing technical founders in healthcare, enterprise AI and deep/industrial tech; 75+ companies, 5 unicorns.

Indicator Ventures

Venture capital

Boston, Massachusetts, USA


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services · Consumer & Retail

Backs high-velocity founders at the pre-seed and seed stage.

Inovo VC

Venture capital

Warsaw, Poland


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences

Backs ambitious CEE founders targeting large markets with products 10x better than alternatives.

IQ Capital

Venture capital

London, UK


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Industrials & Manufacturing · Energy & Utilities

Backs European deep-tech founders building frontier-technology companies that disrupt industrial norms (200+ founders since 2005).

M25

Venture capital

Chicago, Illinois, USA


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services · Industrials & Manufacturing · Transportation & Logistics

Analytical, high-volume pre-seed/seed VC backing go-to-market founders across the Greater Midwest.

monashees

Venture capital

Sao Paulo, Brazil


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services · Consumer & Retail

Backs bold technology-driven Latin American founders building category-defining, globally scaling companies.

Nina Capital

Venture capital

Spain


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences

Invests in need-driven founders transforming healthcare through information technology.

OVO Fund

Venture capital

Menlo Park, USA


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services

Backs founders at the earliest 'negative one to zero' stage, before product-market fit.

oxford capital

Venture capital

Oxford, UK


Stages

GrowthPre-seedSeedSeries BSeries C

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services

Partners with exceptional founders and high-potential scale-ups across the UK from pre-seed through growth.

SmartGateVC

Venture capital

Glendale, CA, USA


Stages

GrowthPre-seedSeedSeries BSeries C

Sectors

Software & Internet · Healthcare & Life Sciences

Invests at the edge where science and entrepreneurship meet, backing industry-defining ideas on day one.

TA Ventures

Venture capital

Kyiv, Ukraine (global)


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services

Global early-stage VC (founder Viktoriya Tigipko) backing pre-seed and seed technology startups across health, fintech and B2B software.

tba network

Venture capital

Brixen (Bressanone), Italy


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services · Energy & Utilities · Real Estate · Education · +1 more

Non-profit business angel network backing Alpine-region founders with risk capital and expertise.

Ubiquity Ventures

Venture capital

San Francisco, CA


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Industrials & Manufacturing

Seed-stage venture firm making early, non-consensus bets on technical founders building 'software beyond the screen' and physical-AI/deeptech companies.

Union Labs Ventures

Venture capital

San Mateo, California, US


Stages

Pre-seedSeed

Sectors

Software & Internet · Healthcare & Life Sciences · Consumer & Retail · Industrials & Manufacturing

Deep-tech seed fund that co-creates companies and writes first institutional checks for founders applying hard technologies to industrial, climate, health and AI problems.

Yoo & Co Accelerators

Venture capital

Phoenix, AZ


Stages

Pre-seedSeed

Sectors

Healthcare & Life Sciences

Phoenix accelerator making small pre-seed investments into healthcare and life-sciences startups moving beyond the incubator stage.

ACT Venture Partners

Venture capital

Europe


Stages

Pre-seedSeed

Sectors

Healthcare & Life Sciences

Backs technical founders solving foundational deep-tech problems at pre-seed/seed with hands-on support on hiring, grants and partnerships.

AltaIR Capital

Venture capital

San Francisco, United States


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services

Early-stage VC investing in productivity tools, AI, SaaS, fintech, insurtech and digital health across the US, Europe and Israel.

Congress Avenue Ventures

Venture capital

Manchester, New Hampshire, USA


Stages

GrowthPre-seedSeedSeries BSeries C

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services

Alumni Ventures fund co-investing alongside top VCs for the University of Texas alumni community.

eHealthVentures

Venture capital

Israel


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences

Early-stage digital health fund and venture builder leveraging an alliance of strategic healthcare partners.

Episode 1 Ventures

Venture capital

London, United Kingdom


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services · Industrials & Manufacturing · Transportation & Logistics

Backs UK pre-seed/seed B2B software founders and helps them reach a successful Series A.

Great Oaks Venture Capital

Venture capital

New York, NY, United States


Stages

Pre-seedSeedSeries A

Sectors

Software & Internet · Healthcare & Life Sciences · Financial Services

One of the most active NY-based seed investors, partnering with founders at the earliest stage to build enduring businesses.

9 more pre-seed investors in healthcare and life sciences

Listed by name and head office. Full profiles are in the searchable directory.

  • Grove Ventures · Israel
  • Hummingbird Ventures · London, United Kingdom
  • Hypothesis · United States
  • Illinois Ventures · Champaign, Illinois, USA
  • New Stack Ventures · Chicago, Illinois, USA
  • nextgen venture partners · Washington, D.C., USA
  • Oceans · New York, USA
  • Prime Venture Partners · India
  • Sandalphon Capital · Chicago, Illinois, USA

Twenty of these are worth your time. The rest are not.

A sector list tells you who invests here. It does not tell you which of them writes cheques your size, at your stage, right now. Run the free valuation and we rank this list against your own numbers, then show you how many fit before you pay anything.

Other stages in healthcare and life sciences

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Counts are as of 2026-09-27; the list above is loaded live, so it can differ if firms have been added or removed since. Sector and stage focus is as stated by the firm. Firms wanting a correction can get in touch.